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Literatur

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The binding of apobec-1 to mammalian apoB RNA is stabilized by the presence of complementation factors which are required for post-transcriptional editing.
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19. Greeve J, Jona VK, Chowdhury NR, Horwitz MS, Chowdhury JR (1996)
Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and Watanabe heritable hyperlipidemic rabbits.
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21. Greeve J, Navaratnain N, Scott J (1991)
Characterization of the apolipoprotein B mRNA editing enzyme: no similarity to the proposed mechanism of RNA editing in kinetoplastid protozoa
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22. Hadjiagapiou C, Giannoni F, Funahashi T, Skarosi SF, Davidson NO (1994)
Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein.
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23. Harris SG, Smith HC (1992)
In vitro apolipoprotein B mRNA editing activity can be modulated by fasting and refeeding rats with a high carbohydrate diet.
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24. Hersberger M, Innerarity TL (1998)
Two efficiency elements flanking the editing site of C 6666 in the Apolipoprotein B mRNA support mooring-dependent editing.
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Developmental and age-related changes in apolipoprotein B mRNA editing in mice.
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Developmental and age-related changes in apolipoprotein B mRNA editing in mice
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26. Hirano K, Min J, Funahashi T, Baunoch DA, Davidson NO (1997)
Characterization of the human apobec-1 gene: expression in gastrointestinal tissues determined b'y alternative splicing with production of a novel truncated peptide.
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Cloning and characterization of the rat ap obec-1 gene: a comparative analysis of gene structure and promoter usage in rat and mouse.
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28. Hirano K, Young SG, Farese RV Jr, Ng J, Sande E, Warburton C, Powell-Braxton LM, Davidson NO (1996)
Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48.
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Site-specific creation of uridine from eytidine in apolipoprotein B mRNA.
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30. Hughes SD, Ruoy D, Navaratnam N, Scott J, Rubin EM (1996)
Gene transfer of cytidine deaminase apobec-1 lowers lipoprotein(a) in transgenic mice and induces apolipoprotein B editing in rabbits.
Hum Gene Ther 7(1):39-49

31. Ince TA, Scotto KW (1995)
A conserved downstream element defines a new class of RNA Polymerase 11 promoters.
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33. Innerarity TL, Bostrom K (1991)
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The mechanism of ApoB mRNA editing is deamination.
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Hepatic expression of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (apobec-1) aineliorates hypercholesterolemia in LDL receptor-deficient rabbits.
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37. Lau PP, Cahill DJ, Zhu HJ, Chan L (1995)
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38. Lau PP, Xiong WJ, Zhu HJ, Chen SH, Chan L (1991)
Apolipoprotein B mRNA editing is an intranuclear event that occurs posttranscriptionally coincident with splicing and polyadenylation.
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39. Lau PP, Zhu HJ, Nakamuta M, Chan L (1994)
Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal lokalization of its gene.
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40. Lau PP, Zhu HJ, Nakamuta M, Chan L (1997)
Cloning of an Apobec 1 binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing.
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41. Leighton JK, Joyner J, Zamarripa J, Deines M, Davis R (1999)
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42. Levy E, Sinnet D, Thibault, L, Nguyen TD, Delvin E, Menard D (1996)
Insulin modulation of newly synthesized apolipoprotein B1OO and B48 in human fetal intestine: gene expression and mRNA editing are not involved.
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43. Lopez-Miranda J, Kam N, Osada J, Rodriguez C, Femandez P, Contois J, Schaefer EJ, Ordovas JM (1994)
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44. Lorentz A, Plonne D, Schulze HP, Dargel R (1996)
Dexamethasone enhanced by insulin, but not by thyroid hormones stimulates apolipoprotein B mRNA editing in cultured rat hepatocytes depending on the developmental stage.
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45. MacGinnitie AJ, Anant S, Davidson NO (1995)
Mutagenesis of apobec-1, the catalytic subunit of the mammalian apoliipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity.
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46. Morrison JR, Paszty C, Stevens ME, Hughes SD, Forte T, Scott J, Rubin EM (1996)
Apolipoprotein B mRNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism.
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47. Nakamuta M, Chang BHJ, Zsigmond E, Kobayashi K, Lei H, Ishida BY, Oka K, Li E, Chan L (1996)
Complete phenotypic characterization of apobec-1 knockout mice with a wild-type genetic Background and a human apolipoprotein B transgenic background, and restoration of apolipoprotein B mRNA editing by somatic gene transfer of Apobec-1.
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48. Nakamuta M, Oka K, Krushkal J, Kobayashi K, Yamamoto M, Li WH, Chan L (1995)
Alternative mRNA splicing and differential promoter utilization detennine tissue-specific expression of the apolipoprotein B mRNA editing enzyme in mice.
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49. Nassir F, Blanchard RK, Mazur A, Cousins RJ, Davidson NO (1996)
Apolipoprotein B mRNA editing is preserved in the intestine and liver of zinc-deficient rats.
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50. Nassir F, Giannoni F, Mazur A, Rayssiguier Y, Davidson NO (1996)
Increased hepatic synthesis and accumulation of plasma apolipoprotein B100 in copperdeficient rats does not result from modification in apolipoprotein B mRNA editing.
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51. Navaratnam N, Fujino T, Bayliss J, Jarmuz A, How A, Richardson N, Somasekaram A, Bhattacharya S, Carter C, Scott J (1998)
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52. Navaratnam N, Morrison JR, Battacharya S, Patel D, Funahashi T, Giannoni F, Teng BB, Davidson NO, Scott J (1993)
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53. Osuga J, Yagyu H, Ohashi K, Harada K, Yazaki Y, Yamada N, Ishibashi S (1997)
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54. Patterson AP, Tennyson GE, Hoeg JM, Sviridov DD, Brewer HB (1992)
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55. Powell LM, Wallis SC, Pease RJ, Edwards YH, Knott TJ, Scott J (1987)
A novel form of tissue-specific RNA processing produces Apolipoprotein B48 in intestine.
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56. Powell-Braxton L, Veniant M, Latvala RD, Hirano KI, Won WB, Ross J, Dybal N, Zlot CH, Young SG, Davidson NO (1998)
A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low fat chow diet.
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57. Qian X, Balestra ME, Innerarity TL (1997)
Two distinct TATA-less promoters direct tissue-specific expression of the rat apo-B editing catalytic polypeptide 1 gene.
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58. Reaves SK, Fanzo JC, Wu JY, Wang YR, Wu YW, Zhu L, Lei KY (1999)
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59. Reaves SK, Hoogeveen RC, Wang YR, Wu JY, Lei KY (1996)
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60. Richardson N, Navaratnam N, Scott J (1998)
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61. Schock D, Kuo SR, Steinburg MF, Bolognino M, Sparks JD, Sparks CE, Smith HC (1996)
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62. Scott J, Navaratnain N, Carter C (1999)
Molecular modelling of the biosynthesis of the RNA-editing enzome APOBEC-1, responsible for generating the alternative forms of apolipoprotein B.
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63. Seishima M, Bisgaier CL, Davies SL, Glickman RM (1991)
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64. Shah RR, Knott TJ, Legros JE, Greeve JC, Scott J (1991)
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65. Sjoeberg A, Oscarsson J, Bostroem K, Innerarity TL, Eden S, Olofsson SO (1992)
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66. Sowden MP, Eagleton MJ, Smith HC (1998)
Apolipoprotein B RNA sequence 3' of the mooring sequence and cellular sources of auxiliary factors determine the location and extent of promiscous editing.
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67. Sowden M, Hanun JK, Smith HC (1996)
Overexpression of Apobec-1 results in mooring sequence-dependent promiscuous RNA editing.
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68. Teng BB, Burant CF, Davidson NO (1993)
Molecular cloning of an apolipoprotein B messenger RNA editing protein.
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69. Teng B, Ishida B, Forte TM, Blumenthal S, Song LZ, Gotto AM Jr, Chan L (1997)
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70. Teng BB, Ochsner S, Zhang Q, Soman KV, Lau PP, Chan L (1999)
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71. Teng BB, Verp M, Salomon J, Davidson NO (1990)
Apolipoprotein B messenger RNA editing is developmentally regulated and widely expressed in human tissues.
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72. Thomgate F, Raghow R, Wilcox HG, Wemer CS, Heimberg M, Elam MB (1994)
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73. von Wronski MA, Hirano KI, Cagen LM, Wilcox HG, Raghow R, Thorngate FE, Heimberg M, Davidson NO, Elam MB (1998)
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74. Wu JF, Semenkovic CF, Chen SH, Li WH, Chan L (1990)
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75. Wu Y, Teng BB, Brandt ML, Piedra PA, Liu J, Chan L (1999)
Normal perinatal rise in serum cholesterol is inhibited by hepatic delivery of adenoviral vector expressing Apobec- 1 in rabbits.
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76. 'Yamanaka S, Balestra ME, Ferrel LD, Fan J, Arnold KS, Taylor S, Taylor JM, Innerarity TL (1995)
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.
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77. Yainanaka S, Poksay KS, Amold KS, Innerarity TL (1997)
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apob mRNA-editing enzyme.
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78. Yamanaka S, Poksay KS, Balestra ME, Zeng GQ, Innerarity TL (1994)
Cloning and mutagenesis of the rabbit apob mRNA editing protein.
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79. Yamanaka S, Poksay KS, Driscoll DM, Innerarity TL (1996)
Hyperediting of multiple cytidines of apolipoprotein mRNA by apobec-1 requires auxiliary protein(s) but not a mooring sequence motif.
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80. Yang Y, Kovalski K, Smith HC (1997)
Partial characterization of the auxiliary factors involved in apolipoprotein B mRNA editing through APOBEC- 1 affinity chromatography.
J Biol Chem 272(44):27700-27706


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