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DC Element | Wert | Sprache |
---|---|---|
dc.contributor.advisor | Schmidt-Chanasit, Jonas | - |
dc.contributor.author | Tomazatos, Alexandru | - |
dc.date.accessioned | 2020-10-27T11:39:23Z | - |
dc.date.available | 2020-10-27T11:39:23Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://ediss.sub.uni-hamburg.de/handle/ediss/8646 | - |
dc.description.abstract | Table of Contents Abstract ....................................................................................................................................... 1 Zusammenfassung.................................................................................................................... 4 Acknowledgements.................................................................................................................. 7 List of Abbreviations ............................................................................................................. 10 List of Figures .......................................................................................................................... 14 List of Tables ........................................................................................................................... 18 1 Introduction .......................................................................................................................... 19 1.1 Background ........................................................................................................................ 19 1.2 Arbovirus surveillance in Europe ................................................................................. 26 1.2.1 Arbovirus surveillance in Romania..................................................................................... 28 1.3 Arboviruses relevant to public health in Europe ....................................................... 30 1.3.1 Mosquito-borne viruses ......................................................................................................... 30 1.3.2 Tick-borne viruses .................................................................................................................. 34 1.3.3 Culicoides-borne viruses ........................................................................................................ 37 1.4 The importance of vector feeding patterns.................................................................. 39 1.4.1 Xenosurveillance: disease identification using blood meals ......................................... 41 1.5 Study rationale and aims................................................................................................. 42 1.6 List of publications........................................................................................................... 45 2 Additional Chapter: Discovery and Genetic Characterization of Sulina Virus, a Novel Orthonairovirus Infecting Ixodes ricinus Ticks from Danube Delta ............... 47 2.1 Background ........................................................................................................................ 47 2.2 Materials and methods .................................................................................................... 49 2.2.1 Tick sampling and processing .............................................................................................. 49 2.2.2 Sulina virus discovery and genome sequencing............................................................... 49 2.2.3 Prevalence of Sulina virus in ticks ...................................................................................... 50 2.2.4 Virus isolation.......................................................................................................................... 50 2.2.5 Serological screening of engorged ticks and host sera .................................................... 51 2.2.6 Sequence data analysis........................................................................................................... 51 2.3 Results................................................................................................................................. 53 2.3.1 Tick identification, molecular and serological screening of Sulina virus ................... 53 2.3.2 Sulina virus genome ............................................................................................................... 54 2.3.3 Phylogenetic analysis ............................................................................................................. 60 2.4 Discussion .......................................................................................................................... 63 3 General Discussion ............................................................................................................. 69 3.1 Vector surveillance in Danube Delta Biosphere Reserve......................................... 69 3.1.1 Longitudinal mosquito surveillance ................................................................................... 69 8 3.1.2 Species composition of Culicoides biting midges ............................................................ 76 3.2 Detection and characterization of arboviruses ........................................................... 81 3.2.1 West Nile virus: phylogeography of an endemic pathogen ........................................... 81 3.2.2 Letea virus: a reassortant orbivirus discovered in grass snakes (Natrix natrix) ......... 87 3.3 Vectors feeding patterns.................................................................................................. 94 3.3.1 Host-feeding pattern of mosquitoes.................................................................................... 94 3.3.1.1 Xenosurveillance of WNV using mosquito blood meals ........................................... 100 3.3.2 Blood meal analysis of Culicoides biting midges ........................................................... 102 4 Conclusions and outlook ................................................................................................. 107 5 References ........................................................................................................................... 110 Appendix ................................................................................................................................ 142 | en |
dc.language.iso | en | de_DE |
dc.publisher | Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky | - |
dc.relation.isbasedon | Viruses 2020, 12, 243; Parasites Vectors (2020) 13:79; Viruses 2019, 11, 1159; Parasites & Vectors (2018) 11:392 | - |
dc.rights | http://purl.org/coar/access_right/c_abf2 | de_DE |
dc.subject | One Health | en |
dc.subject | Culicoides | en |
dc.subject | Virusentdeckung | en |
dc.subject.ddc | 570: Biowissenschaften, Biologie | de_DE |
dc.title | Arthropod-borne Viruses in Danube Delta: Surveillance, Phylogeography and Vector Feeding Patterns | en |
dc.title.alternative | Von Arthropoden übertragene Viren im Donaudelta: Überwachung, Phylogeographie und Vektorfütterung | de |
dc.type | doctoralThesis | - |
dcterms.dateAccepted | 2020-08-19 | - |
dc.rights.cc | No license | de_DE |
dc.rights.rs | http://rightsstatements.org/vocab/InC/1.0/ | - |
dc.subject.bcl | 42.13: Molekularbiologie | de_DE |
dc.subject.bcl | 42.32: Virologie | de_DE |
dc.subject.bcl | 42.36: Parasitologie | de_DE |
dc.subject.bcl | 42.90: Ökologie: Allgemeines | de_DE |
dc.subject.gnd | Viren | - |
dc.subject.gnd | Gliederfüßer | - |
dc.subject.gnd | Stechmücken <Familie> | - |
dc.subject.gnd | Zecken | - |
dc.subject.gnd | Donaudelta | - |
dc.subject.gnd | Rumänien | - |
dc.subject.gnd | Zoonose | - |
dc.type.casrai | Dissertation | - |
dc.type.dini | doctoralThesis | - |
dc.type.driver | doctoralThesis | - |
dc.type.status | info:eu-repo/semantics/publishedVersion | de_DE |
dc.type.thesis | doctoralThesis | de_DE |
tuhh.opus.id | 10747 | - |
tuhh.opus.datecreation | 2020-09-29 | - |
tuhh.type.opus | Dissertation | - |
thesis.grantor.department | Biologie | de_DE |
thesis.grantor.place | Hamburg | - |
thesis.grantor.universityOrInstitution | Universität Hamburg | de_DE |
dcterms.DCMIType | Text | - |
tuhh.note.extern | Quelle: Viruses 2020, 12, 243; Parasites Vectors (2020) 13:79; Viruses 2019, 11, 1159; Parasites & Vectors (2018) 11:392 | de_DE |
dc.identifier.urn | urn:nbn:de:gbv:18-ediss-86451 | - |
item.fulltext | With Fulltext | - |
item.creatorGND | Tomazatos, Alexandru | - |
item.advisorGND | Schmidt-Chanasit, Jonas | - |
item.creatorOrcid | Tomazatos, Alexandru | - |
item.grantfulltext | open | - |
item.languageiso639-1 | other | - |
Enthalten in den Sammlungen: | Elektronische Dissertationen und Habilitationen |
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Dissertation.pdf | ef03e8886e98c25097c22987a2af39d2 | 9.17 MB | Adobe PDF | Öffnen/Anzeigen |
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